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The effects of thyrotoxicosis on the contractile properties and development of muscle fatigue in the slow soleus (SOL) and fast extensor digitorum longus (EDL) muscles were examined in rats given 3 mg of L thyroxine and 1 mg of L triiodothyronine per kilogram of diet for 6 weeks. The hormone treatment produced significant decreases in the contraction time Designer Replica Bags, one half relaxation time, and twitch tension in the SOL, while the peak rate of tension development (+ dP/dt) and decline ( dP/dt) in this muscle were elevated. Additionally, the forcefrequency curve was shifted to the right and, thus, resembled the curve of a normal fast twitch muscle.
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